926 research outputs found

    Book Review: Number One Realist: Bernard Fall and Vietnamese Revolutionary Warfare

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    Author: Nathaniel L. Moir Reviewed by John A. Nagl, professor of warfighting studies, US Army War College Counterinsurgency expert John A. Nagl reviews the “long-overdue” biography of the American political scientist Bernard Fall who, as Nagl writes, was “always a couple years ahead of informed US public opinion” about the Vietnam War. Author Nathaniel L. Moir’s experience as an Afghanistan War veteran informs this examination of one of the most “contentious” topics in American history, and the intersection here of Dr. Nagl’s, Moir’s, and Fall’s expertise provides powerful insights about the persistent question of how best to approach counterinsurgency.https://press.armywarcollege.edu/parameters_bookshelf/1034/thumbnail.jp

    Why America’s Army Can’t Win America’s Wars

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    Since achieving victory in World War II, the United States military has a less than enviable combat record in irregular warfare. Through a detailed historical analysis, this article provides perspective on where past decisions and doctrines have led to defeat and where they may have succeeded if given more time or executed differently. In doing so, it provides lessons for future Army engagements and argues that until America becomes proficient in irregular warfare, our enemies will continue to fight us at the lower levels of the spectrum of conflict, where they have a good chance of exhausting our will to fight

    A Call to Action: Lessons from Ukraine for the Future Force

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    Fifty years ago, the US Army faced a strategic inflection point after a failed counterinsurgency effort in Vietnam. In response to lessons learned from the Yom Kippur War, the United States Army Training and Doctrine Command was created to reorient thinking and doctrine around the conventional Soviet threat. Today’s Army must embrace the Russo-Ukrainian conflict as an opportunity to reorient the force into one as forward-thinking and formidable as the Army that won Operation Desert Storm. This article suggests changes the Army should make to enable success in multidomain large-scale combat operations at today’s strategic inflection point

    Review and Reply: On “Why America’s Army Can’t Win America’s Wars” (part 2)

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    This commentary responds to John A. Nagl’s article, “Why America’s Army Can’t Win America’s Wars,” published in the Autumn 2022 issue of Parameters (vol. 52, no. 3)

    Review and Reply: On “Why America’s Army Can’t Win America’s Wars” (part 1)

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    This commentary responds to John A. Nagl’s article, “Why America’s Army Can’t Win America’s Wars,” published in the Autumn 2022 issue of Parameters (vol. 52, no. 3)

    Genetic variation and relationships among spring camelina (Camelina sativa, Brassicaceae) accessions of different origin

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    Camelina sativa L. is one of the oldest crops of the Brassicaceae family, first domesticated in the region of south-eastern Europe. It has regained interest as a very promising alternative oilseed crop with broad adaptability, a wide range of tolerances to pests and diseases, and low-input requirements. The genetic diversity in spring camelina proved to be limited, so the identification and characterization of genetic variations is considered very useful for development of efficient breeding programmes. The aim of the study was to use SSR markers in order to investigate genetic variation of twenty spring camelina accessions and their relatedness. Forty-five individual samples were taken from each accession and used for amplification of SSR markers P4C11, P6E4 and LIB19. The accessions expressed different levels of genetic variation, AMOVA (analysis of molecular variance) showed that 64% of the total genetic variation was attributed to variance within accessions. Genetic distance analysis indicated that there was overlapping in certain breeding programs and exchange of breeding germplasm

    Construction of plant transformation vectors carrying beet necrotic yellow vein virus coat protein gene (i) - transformation vectors

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    Coat protein gene of beet necrotic yellow vein virus (BNYVV) was isolated from inoculated sugar beet roots and leaves of Chenopodium quinoa and Tetragonia expansa, by RT-PCR and imuno capture RT-PCR. Specific primers were made to complement coat protein gene and untranslated leader sequence, so that two fragments were obtained: long (731 bp), which contained coat protein gene and leader sequence, and short (587 bp), with coat protein gene. Fragments were cloned in two plant transformation vectors: pCAMBIA 3301M and pCAMBIA 1304M, which were modified by removing multicloning site and NcoI restriction site at the 5' end of the reporter genes. Vector pC3301M had bar gene which confers resistance against the herbicide gluphosinate ammonium as selectable marker, and pC1304M had gene for resistance to antibiotic hygromycin. Three constructs were made from each vector: CPL, containing coat protein gene with leader sequence; CPS with gene for coat protein, and CPSas with coat protein gene in antisense orientation. All constructs were transfered to Agrobacterium tumefaciens strain LBA4404

    Army Professionalism, the Military Ethic, and Officership in the 21st Century

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    The authors address what they—and many others—perceived to be a decline in military professionalism in the Army officer corps. The authors first describe the ethical, technical, and political components of military professionalism and then address the causes for the decline. They conclude by proposing a set of principles which, if adhered to, will reinvigorate the vision of the officer corps and motivate the corps to selfless service.https://press.armywarcollege.edu/monographs/1145/thumbnail.jp

    Tolerability of inhaled N-chlorotaurine in an acute pig streptococcal lower airway inflammation model

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    <p>Abstract</p> <p>Background</p> <p>Inhalation of N-chlorotaurine (NCT), an endogenous new broad spectrum non-antibiotic anti-infective, has been shown to be very well tolerated in the pig model recently. In the present study, inhaled NCT was tested for tolerability and efficacy in the infected bronchopulmonary system using the same model.</p> <p>Methods</p> <p>Anesthetized pigs were inoculated with 20 ml of a solution containing approximately 10<sup>8 </sup>CFU/ml <it>Streptococcus pyogenes </it>strain d68 via a duodenal tube placed through the tracheal tube down to the carina. Two hours later, 5 ml of 1% NCT aqueous solution (test group, n = 15) or 5 ml of 0.9% NaCl (control group, n = 16) was inhaled via the tracheal tube connected to a nebulizer. Inhalation was repeated every hour, four times in total. Lung function and haemodynamics were monitored. Bronchoalveolar lavage samples were removed for determination of colony forming units (CFU), and lung samples for histology.</p> <p>Results</p> <p>Arterial pressure of oxygen (PaO<sub>2</sub>) decreased rapidly after instillation of the bacteria in all animals and showed only a slight further decrease at the end of the experiment without a difference between both groups. Pulmonary artery pressure increased to a peak 1-1.5 h after application of the bacteria, decreased in the following hour and remained constant during treatment, again similarly in both groups. Histology demonstrated granulocytic infiltration in the central parts of the lung, while this was absent in the periphery. Expression of TNF-alpha, IL-8, and haemoxygenase-1 in lung biopsies was similar in both groups. CFU counts in bronchoalveolar lavage came to 170 (10; 1388) CFU/ml (median and 25 and 75 percentiles) for the NCT treated pigs, and to 250 (10; 5.5 × 10<sup>5</sup>) CFU/ml for NaCl treated pigs (p = 0.4159).</p> <p>Conclusions</p> <p>Inhaled NCT at a concentration of 1% proved to be very well tolerated also in the infected bronchopulmonary system. This study confirms the tolerability in this delicate body region, which has been proven in healthy pigs previously. Regarding efficacy, no conclusions can be drawn, mainly because of the limited test period of the model.</p
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